文献类型     学术论文
标    题     Rapid enhancement of f32-interferon/B-cell differentiation factor BSF-2 gene expression in human fibroblasts by diacylglycerols and the calcium ionophore A23187
著    者     PRAVINKUMAR B. SEHGAL; ZENTA WALTHER; IGOR TAMM
机    构     T he Rockefeller University
集合名     Proc. Nati. Acad. Sci. USA
年 1987
月 6
卷 84
地    域     New York, NY
文件大小     1.23 MB
描    述     The expression in human fibroblasts of the p2-interferon (IFN-.82) gene, which is now recognized to be identical to the gene encoding B-cell differentiation factor BSF-2, is enhanced by several cytokines that affect cell growth (tumor necrosis factor, interleukin 1, platelet-derived growth factor, and fi1-interferon). We have examined the possibility that IFN-.82 gene expression is regulated through activation, by diacylglycerol, of the protein kinase C pathway. The synthetic diacylglycerols 1,2...More

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